In this work, the effect of temperature on nanofiltration membrane properties and the resulting effect on ion and solvent transport through the membrane are studied, using three different feed compositions. Effect of protein and solution properties on the donnan. Role of ionic charge density in donnan exclusion of. Gibbsdonnan equilibrium and the membrane potential youtube. Effect of electric field intensity on the performance of. Nanofiltration nf is a relatively recent membrane filtration process used most often with low total dissolved solids water such as surface water and fresh groundwater, with the purpose of softening polyvalent cation removal and removal of disinfection byproduct precursors such as natural organic matter and synthetic organic matter nanofiltration is also becoming more widely used in food. Ch15 engineering sciences and general subjects 1,318 views. Consequently, donnan exclusion effect, which is determined by the electric charge of membrane surface, is generally proposed as the predominated mechanism for salts removal by nanofiltration. Theoretical modeling has been developed to predict excipient and ph changes as a result of the donnan effect in monoclonal antibody mab processes. The gibbsdonnan effect is a name for the behaviour of charged particles near a. By nanofiltration the organic molecules are retained. One challenge associated with highconcentration formulations is increased electrostatic interaction between proteins and excipients.
The usual cause is the presence of a different charged substance that is unable to pass through the membrane and. Protein concentration and diafiltration by tangential flow. The subjects addressed in this chapter should serve as the basic foundation for a broader understanding of ro and nf processes as applied to potable water, industrial process water, tertiary wastewater, and reclaimed water. Nanofiltration of a solution containing four monovalent ions has been carried out to assess the donnan steric and dielectrical exclusion pore model dsdepm. Effect of solution chemistry on water softening using charged nanofiltration membranes by chichung hsiung, chihshen chen, chingjung chuang, dipankar nanda, kuolun tung, ruohchyu ruaan, tienhwa wu and yanche chiang. Donnan effect repulsion or attraction effect due to membrane potential and dielectric exclusion. Enhancement of the donnan effect through capacitive ion increase using an electroconductive rgocnt nanofiltration membrane chengzhi hu, abc zhongtao liu, a xinglin lu, c jingqiu sun, ab huijuan liu ab and jiuhui qu ab. In this model, donnan equilibrium and steric effect are responsible for the ionic partitioning between solution and membrane. Utilization of the donnan effect for improving electrolyte separation with nanofiltration membranes. The biopharmaceutical industry is targeting highconcentration protein formulations to enable subcutaneous administrations. Utilization of the donnan effect for improving electrolyte separation. Role of charge donnan exclusion in removal of arsenic.
This modeling includes the temperature dependence of the three modes of solute transport, namely the convective, electromigrative, and diffusive modes, and the three mechanisms of solute exclusion, namely donnan. Development of nanofiltration membrane separation prediction system. Retention measurements were carried out as a function of the permeate flux for uncharged solutes, which allowed characterization of the membranes in terms of an effective. How the gibbsdonnan equilibrium forms an electrical charge on a cell membrane. Present article describes about the preparation of nanofiltration nf composite membranes by a simple chemical treatment to the polymeric membrane composed of poly isobutylenealtmaleic anhydride. Nanofiltration ultrafiltration microfiltration conventional filtration gas perm membrane distilation organics figure 1. The increased salt removal is obtained by the addition of an ionized polyelectrolyte na salt of polyacrylic acid, pna having a molecular weight of 60 000. The nanofiltration powerpoint slide set provides a brief introduction to the different types of filtration and how they. Nanofiltration membranes, organic membranes, or ceramic membranes can be either dense or porous. Pdf development of nanofiltration membrane separation. The results are interpreted qualitatively by the donnan exclusion mechanism, which takes the charge effects into account. Utilization of the donnan effect for improving electrolyte. The donnan effect on excipient levels has received significant attention in recent years. The possibility of utilizing the donnan effect to enhance nacl removal from a solution of a watersoluble organic dye procion red he7b, ici using a nanofiltration membrane was examined.
We used an extended solutiondiffusion model that incorporates donnan electrostatic exclusion of ions and unhindered advection due to imperfections, and measurements of charge density in the polyamide active layers of reverse osmosis ro and nanofiltration nf membranes, to predict the rejection of a strong electrolyte i. The donnan effect which is named after the british chemist frederick george donnan donnan 1911, 1995 is related to the presence of impermeant ions i. Analysis of the salt retention of nanofiltration membranes. Nanofiltration is also used when anaerobic groundwater has a high value of organic matter. The main objective of this study is to examine how the charge densities of four monovalent anionsfluoride f, chloride cl, bromide br, and nitrate no3influence their donnan charge exclusion by a charged nanofiltration nf membrane. Effect of temperature on ion transport in nanofiltration. Abstract experimental and modelling analysis is presented for characterization of polymeric nanofiltration membranes. In general, even low molecular weight organics 200 gmol and multivalent ions are highly retained, while monovalent ions are retained to a smaller extent.
After composition, anhydride functionality was converted to diacid functionality by hydrolysis using sodium hydroxide solution. Effect of solution chemistry on water softening using. The pbi ro hfm was positively surface charged in acidic conditions ph donnan effect during the diafiltration and concentration of proteins in solutions containing monovalent and divalent ions were derived. Effect of ion sizes on separation characteristics of. If you are a society or association member and require assistance with obtaining online access instructions please contact our journal customer services team. Arsenic in drinking water is a major health risk in many places in the world. Pdf role of charge donnan exclusion in removal of arsenic. Research paper by daniele vezzani and serena bandini. The effect of polymerization time on pore size is not significant for reaction times less than 120 s but the effective thicknessporosity seems to be increasing proportionally with polymerization time. Ultrafiltration membrane for effective removal of chromium. Enhancement of the donnan effect through capacitive ion increase using an electroconductive rgocnt nanofiltration membrane.
Negatively charged nanofiltration membrane prepared with interfacial polymerization method has high rejection to anion with high valence because of donnan effect. Semiat department of chemical engineering, technionisrael institute of technology, haifa 32000, israel received 4 may 1995. Even surface water can be treated with nanofiltration. This model accounts for the transport phenomena occurring inside the membrane through the appropriate ion sizes.
Nernst equation and calculations of membrane potentials duration. Theoretical performance of nanofiltration membranes for. Request pdf enhancement of the donnan effect through capacitive ion increase using an electroconductive rgocnt nanofiltration membrane graphene oxide go based membrane in desalination is. The gibbs donnan effect also known as the donnan s effect, donnan law, donnan equilibrium, or gibbs donnan equilibrium is a name for the behaviour of charged particles near a semipermeable membrane that sometimes fail to distribute evenly across the two sides of the membrane.
Nanofiltration is a promising technology which has many applications in water and wastewater. These proteinbound charges are ph dependent, and in the physiological ph range, proteins oveall carry a net negative charge. The results are interpreted qualitatively by the donnan exclusion mechanism, which takes the charge effects into. Endre nagy, in basic equations of the mass transport through a membrane layer, 2012. Effect of temper ature on ion tr anspor t in nanofiltr. Read acid separation with nanofiltration effect of electrolyte strength and donnan forces, desalination on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. The objective of the present work was to investigate the efficacy of indigenously developed polyacrylonitrile pan based ultrafiltration uf membrane for. Higher pressure and concentration showed positive response, while presence of competing compound showed negative response on phosphorus rejection. Enhancement of the donnan effect through capacitive ion. Nanoparticletemplated nanofiltration membranes for. However, for economic reasons and reasons of safety, excessive doses of acid or base should not be utilized. To better understand the mechanisms of arsenic removal by the polymeric membrane, its surface charge, pore size, and separation behavior for several salt solutions nacl, cacl 2, and na 2 so 4 were first investigated. Enhancement of the donnan effect through capacitive ion increase.
Further, membrane was characterized by atrir, dsc and sem. Experimental evidence is given for several salt solutions and saccharide solutions. The new donnan models obey mass conservation laws, account for the buffering capacity of proteins, and account for protein. Accordingly, the aluminum concentration in the leached solution is typically limited, thus the recovered aluminum cannot be directly reused as a coagulant. Nanofiltration efficiency in nitrate removal from groundwater. The removal of arsenic from water by a negatively charged loose porous nanofiltration nf membrane was investigated. The effect of the ion size on salt rejection is investigated using the donnan steric pore model dspm. Nanofiltration nf membranes with ultrahigh permeance and high rejection are highly beneficial for efficient desalination and wastewater treatment.
Donnan charge and steric size exclusion effects in. Such administration can provide better patient convenience than intravenous administration. Performance of pspimappees nanofiltration membranes. Preparation of polybenzimidazole hollowfiber membranes. Nanofiltration can also be used when the hardness of the water is too high, calcium and magnesium ions are retained by nanofiltration. Results showed that phosphorus removal efficiency for nanofiltration is high 95% and it can produce an effluent containing less than 0. The mechanism for separation can be explained in terms of charge effects andor size effects.
Pdf use of nanofiltration membranes to concentrate and. In many instances, from ultrafiltration of proteins to ion exchange chromatography, the ph of the buffer. As permeate composition influences the transport across the membrane, the resulting equation system is implicit. The teacher reading is recommended prior to presenting the nanofiltration powerpoint slides and other activities. The recovery of aluminum from water purification sludge is usually performed by making the solution acidic or basic. Nanofiltration is a pressuredriven membrane process that lies between ultrafiltration and reverse osmosis in terms of its ability to reject molecular or ionic species. The negative effect 334 of salinity and ic speciation on f retention was attributed to charge screening and donnan effect 335 51, 54, 55. P is the difference in pressure along the feed channel of the membrane from the inletto the outlet. In this study, arsenic removal by nanofiltration membranes, nf270 and tfcsr2, were evaluated under various initial arsenic concentrations, initial feed ph, ionic strength, applied. Pdf the removal of arsenic from water by a negatively charged loose porous nanofiltration nf.
Modeling the effect of charge density in the active layers. Three commercial nanofiltration membranes are used. In this study, new equations for the donnan effect during the diafiltration and concentration of proteins in solutions containing monovalent and divalent ions were derived. The performance of four commercial nanofiltration membranes was analyzed by the donnansteric partitioning pore model dspm that describes solute transport through a membrane using the extended nernstplanck equation. The effect of polymerization reaction time on the membrane characteristics and membrane performance flux and rejection was studied. The solutions were fed through a parallel plate osmotic cell having an area of 200 cm2, fitted with an mpf44 nanofiltration membrane. Nanofiltration is a pressuredriven membrane separation process that falls in between reverse osmosis and ultrafiltration in its separation characteristics. Nanofiltration modeling based on the extended nernst. Potential of nanofiltration for phosphate removal from. P bar p f p r conversion ratio cr is the fraction of the feed side flow that passes through the. Abstractnanofiltration membrane has high flux and rejection to inorganic salts at relative low operation pressure, which is widely used in desalination and wastewater treatment. The ability of the membrane to remove inorganic arsenic. Retention mechanisms in nanofiltration springerlink.
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